Document Detail

The modern management of macroprolactinomas.
MedLine Citation:
PMID:  18411177     Owner:  NLM     Status:  In-Data-Review    
Macroprolactinomas will usually shrink with dopamine agonist therapy, often to within the pituitary fossa; definitive treatment with radiotherapy can then achieve eventual normalization of serum prolactin in the majority of patients. Persistent suprasellar extensions, even when relatively large, can usually be successfully decompressed by the transsphenoidal route. Stalk compression can also give rise to hyperprolactinemia that will normalize with bromocriptine, but tumors causing it will rarely, if ever, show significant shrinkage in response to the drug.
A Grossman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  2     ISSN:  1043-2760     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:    1991 Sep-Oct
Date Detail:
Created Date:  2008-04-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  163-8     Citation Subset:  -    
Department of Endocrinology, St. Bartholomew's Hospital, London ECIA 7BE, United Kingdom.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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