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A moderate intensity exercise program did not increase the oxidative stress in older adults.
MedLine Citation:
PMID:  21236502     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Oxidative damage to lipoproteins, in particular low density lipoprotein (LDL), is known to play a role in a number of diseases associated with aging such as cardiovascular disease (CVD) and dementia. Exercise can alter the balance of oxidative and anti-oxidative species within the human body and may cause oxidative damage to lipoproteins. The purpose of this study was to assess the effect of a moderate intensity exercise program on markers of oxidative stress in older age adults. Parameters of lipoprotein protein and lipid oxidation, and lipoprotein nitration were assessed in aged individuals who undertook a program of moderate physical activity for a period of 8 weeks. There were no significant changes in LDL protein oxidation or nitration which could be attributed to 8 weeks of walking exercise, however, LDL nitration was increased following acute steady state exercise (pre-: 0.34±0.1 vs. post-: 0.44±0.07μm/mg LDL; p=0.04). Walking at moderate intensity caused a significant weight decrease in the exercise group, but did not have any significant effect on VO(2)max. Exercise at this intensity was not harmful and did not increase risk factors for diseases associated with oxidative stress in the participants of the study.
Authors:
Sarah Aldred; Manjit Rohalu
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-12
Journal Detail:
Title:  Archives of gerontology and geriatrics     Volume:  -     ISSN:  1872-6976     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214379     Medline TA:  Arch Gerontol Geriatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
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