Document Detail

A model to induce scattered cell damage in the corneal endothelium.
MedLine Citation:
PMID:  2471949     Owner:  NLM     Status:  MEDLINE    
A model to induce scattered cell damage in the corneal endothelium was set up by shaking a pig cornea in a glass bottle with 0.18% NaCl. Disseminated endothelial-cell losses, whose amounts correlated with the durations of treatment, were observed in the corneas which were shaken for less than 8 min. Following organ culturing for 1 week, most of the corneas still possessed intact endothelia which means that even after the treatment the endothelium still keeps a normal regenerative ability. With this method of design, a good model is provided to study the regeneration of the corneal endothelium.
C P Lin; M Böhnke; J Draeger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmic research     Volume:  21     ISSN:  0030-3747     ISO Abbreviation:  Ophthalmic Res.     Publication Date:  1989  
Date Detail:
Created Date:  1989-07-18     Completed Date:  1989-07-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267442     Medline TA:  Ophthalmic Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  IM    
Department of Ophthalmology, Kaohsiung Medical College, Taiwan, ROC.
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MeSH Terms
Cell Count
Cell Survival
Endothelium, Corneal / injuries*
Models, Biological*
Organ Culture Techniques
Osmolar Concentration
Staining and Labeling
Time Factors

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