Document Detail


A model for the synthesis of chemical compounds in red blood cells, with an application to diabetes.
MedLine Citation:
PMID:  6733235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The amount of a substance produced and stored in red blood cells is modelled as the solution to a first-order differential equation involving the stochastic rate of production of the substance within each cell, the lifespans of the cells, and the birth and death rates of the cells. Estimation of the parameters of the model is outlined for a special case, and the model is fitted to a set of real data taken from clinically diabetic dogs.
Authors:
M L Deaton; J J Higgins; J E Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biometrics     Volume:  40     ISSN:  0006-341X     ISO Abbreviation:  Biometrics     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-07-27     Completed Date:  1984-07-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370625     Medline TA:  Biometrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  77-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Diabetes Mellitus, Experimental / blood*,  metabolism
Dogs
Erythrocyte Aging
Erythrocytes / metabolism*
Hemoglobin A, Glycosylated / analogs & derivatives,  biosynthesis
Models, Biological*
Chemical
Reg. No./Substance:
0/Hemoglobin A, Glycosylated; 0/glucosylated hemoglobin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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