Document Detail


A model-based prediction for transvaginal ultrasonographic identification of early intrauterine pregnancy.
MedLine Citation:
PMID:  1595805     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Our objective was to develop a mathematic model for the prediction of transvaginal ultrasonographic identification of intrauterine gestation as a function of human chorionic gonadotropin titer or gestational age. STUDY DESIGN: In this prospective, descriptive study normal intrauterine pregnancies of 31 patients from the Yale in vitro fertilization and embryo transfer program and infertility clinic were studied. Logistic regression analysis was used to develop a probability curve of transvaginal ultrasonographic detection of intrauterine pregnancy as a function of human chorionic gonadotropin titer or gestational age with a 5 MHz vaginal transducer. RESULTS: A model-based prediction was constructed. It revealed that nearly all intrauterine sacs should be identified by a human chorionic gonadotropin titer of 3000 mIU/ml (first international reference preparation) or by a gestational age of 37 days on the basis of the 5 MHz vaginal transducer. CONCLUSIONS: A model-based prediction for transvaginal ultrasonographic identification of early intrauterine pregnancy is presented that can be readily adapted by individual institutions using their own ultrasonographic equipment and human chorionic gonadotropin assay.
Authors:
B S Shapiro; M Escobar; R Makuch; G Lavy; A H DeCherney
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  166     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-06-26     Completed Date:  1992-06-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1495-500     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut.
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MeSH Terms
Descriptor/Qualifier:
Chorionic Gonadotropin / blood
Embryo Transfer
Female
Fertilization in Vitro*
Gestational Age
Humans
Mathematics
Models, Biological*
Pregnancy
Pregnancy Tests*
Prospective Studies
Regression Analysis
Ultrasonography, Prenatal*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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