Document Detail


A model for acute haemodynamic studies in the ascending aorta in pigs.
MedLine Citation:
PMID:  3252970     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Since data on velocity fields in the ascending aorta downstream of normal aortic valves in pigs have not yet been obtained velocity profiles were visualised using a hot film anemometer needle probe before and after total cardiopulmonary bypass and cold cardioplegic arrest. Furthermore, measurements were made during increased heart rate and cardiac output. A dynamic three dimensional visualisation of velocity fields showed a skewed clockwise rotating velocity profile, developing from peak systole and continuing throughout the systolic deceleration phase. This pattern was consistent regardless of the haemodynamic state. Heart rate was increased to 180 beats.min-1 and cardiac output by a maximum of 91%. It is concluded that the pig model is valuable for haemodynamic studies in the ascending aorta before and after cold cardioplegic arrest and that the velocity profiles found in this study are important basic data for velocity field studies downstream of artificial heart valves implanted in the aortic position.
Authors:
J M Hasenkam; J H Ostergaard; E M Pedersen; P K Paulsen; H Nygaard; B A Schurizek; G Johannsen
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cardiovascular research     Volume:  22     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1989-08-18     Completed Date:  1989-08-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  464-71     Citation Subset:  IM    
Affiliation:
Department of Thoracic and Cardiovascular Surgery, Aarhus Kommunehospital, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aorta / physiology*
Blood Flow Velocity
Cardiac Output
Cardioplegic Solutions
Cardiopulmonary Bypass
Heart Arrest, Induced
Hemodynamics*
Models, Cardiovascular
Pulse
Rheology
Swine / physiology*
Chemical
Reg. No./Substance:
0/Cardioplegic Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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