| The modENCODE Data Coordination Center: lessons in harvesting comprehensive experimental details. | |
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MedLine Citation:
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PMID: 21856757 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The model organism Encyclopedia of DNA Elements (modENCODE) project is a National Human Genome Research Institute (NHGRI) initiative designed to characterize the genomes of Drosophila melanogaster and Caenorhabditis elegans. A Data Coordination Center (DCC) was created to collect, store and catalog modENCODE data. An effective DCC must gather, organize and provide all primary, interpreted and analyzed data, and ensure the community is supplied with the knowledge of the experimental conditions, protocols and verification checks used to generate each primary data set. We present here the design principles of the modENCODE DCC, and describe the ramifications of collecting thorough and deep metadata for describing experiments, including the use of a wiki for capturing protocol and reagent information, and the BIR-TAB specification for linking biological samples to experimental results. modENCODE data can be found at http://www.modencode.org. Database URL: http://www.modencode.org. |
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Authors:
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Nicole L Washington; E O Stinson; Marc D Perry; Peter Ruzanov; Sergio Contrino; Richard Smith; Zheng Zha; Rachel Lyne; Adrian Carr; Paul Lloyd; Ellen Kephart; Sheldon J McKay; Gos Micklem; Lincoln D Stein; Suzanna E Lewis |
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Publication Detail:
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Type: Journal Article Date: 2011-08-19 |
Journal Detail:
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Title: Database : the journal of biological databases and curation Volume: 2011 ISSN: 1758-0463 ISO Abbreviation: Database (Oxford) Publication Date: 2011 |
Date Detail:
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Created Date: 2011-08-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101517697 Medline TA: Database (Oxford) Country: England |
Other Details:
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Languages: eng Pagination: bar023 Citation Subset: IM |
Affiliation:
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Lawrence Berkeley National Laboratory, Genomics Division, 1 Cyclotron Road MS64-121, Berkeley, CA 94720, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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