| The minimum alveolar concentration of nitrous oxide in man. | |
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MedLine Citation:
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PMID: 7201254 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The potency and anesthetic state produced by nitrous oxide alone were investigated in order to clarify its contribution to the effect of other anesthetic agents. Seven volunteers anesthetized with 1.55 atm absolute N2O in a pressure chamber displayed muscle rigidity with jerking movements, labored and rapid breathing, sweating, and dilated pupils. At 1.1 atm absolute N2O, relaxation and quiescence occurred, sweating ceased, and pupil size decreased. Determination of MAC (using tetanic electrical impulses as the noxious stimulus) produced a mean value of 1.04 +/- 0.10 (SE) atm absolute. All subjects complained of nausea and vomiting after anesthesia. |
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Authors:
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T F Hornbein; E I Eger; P M Winter; G Smith; D Wetstone; K H Smith |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 61 ISSN: 0003-2999 ISO Abbreviation: Anesth. Analg. Publication Date: 1982 Jul |
Date Detail:
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Created Date: 1982-08-07 Completed Date: 1982-08-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 553-6 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atmospheric Pressure Dose-Response Relationship, Drug Humans Male Movement / drug effects Nausea / chemically induced Nitrous Oxide / administration & dosage*, adverse effects Pulmonary Alveoli Vomiting / chemically induced |
| Grant Support | |
ID/Acronym/Agency:
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GM-15571/GM/NIGMS NIH HHS; GM-15991/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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10024-97-2/Nitrous Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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