Document Detail

A minimal parametric model of the femur to describe axial elastic strain in response to loads.
MedLine Citation:
PMID:  8843406     Owner:  NLM     Status:  MEDLINE    
Evaluating the state of stress/strain for a given geometry and load in femurs can be done both experimentally, measuring strain at a limited number of locations, and theoretically with finite element models. Another approach is to describe the state of strain with a few synthetic indices. For this purpose the reverse elastic problem (i.e. bone parameters are estimated given the strain distribution and loads) needs to be solved as opposed to the finite element direct problem. Such reverse models can be then used: (1) to describe simply the strain distribution by means of few synthetic indices; (2) to explain the state of strain; and (3) to predict the strain distribution under different loading conditions. Various linear models, characterized by two to five bone related parameters, were tested on (1) 12 femurs, (2) a finite element model, and (3) data taken from the literature, for a total of 43 loading cases. Three and four-parameter models were able to fit the experimental strain distributions with mean squared residuals smaller than 5% of the strain range. The consistency of the model was proved by the repeatability of the parameters estimate for identical femurs. Furthermore, the bone-related coefficients were able to detect the stiffening effect of the implantation of an uncemented stem. Finally, the model can be used for predictive purposes if the parameter estimates are used with different loading conditions.
L Cristofolini; A Cappello; B P McNamara; M Viceconti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical engineering & physics     Volume:  18     ISSN:  1350-4533     ISO Abbreviation:  Med Eng Phys     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-01-09     Completed Date:  1997-01-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9422753     Medline TA:  Med Eng Phys     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  502-14     Citation Subset:  IM    
Department of Electronics, Informatics and Systems, Engineering Faculty, University of Bologna, Italy.
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MeSH Terms
Biomedical Engineering
Femur / anatomy & histology*,  physiology*,  surgery
Linear Models
Models, Anatomic
Models, Biological*
Prostheses and Implants
Reproducibility of Results
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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