| A miniaturized chronic microelectrode drive for awake behaving head restrained mice and rats. | |
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MedLine Citation:
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PMID: 20036690 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present work introduces an electrode microdrive system small enough to be placed into two distinct brain areas in head-fixed mice. To meet the space constraint imposed by the size of mice and the additional presence of a head post, the size and weight of the components were minimized. In the current version, an individual microdrive moves an array of four Reitboeck type electrodes. We report about successful implantation in rats and mice using one or two microdrives. Using two of these devices in individual mice/rats, the recording of parallel single and multi-unit as well as local field potential from prefrontal, motor, somatosensory cortex and hippocampus is demonstrated. The system can be easily constructed with machinery and equipment present in most neurophysiology labs. |
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Authors:
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Florent Haiss; Sergejus Butovas; Cornelius Schwarz |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-29 |
Journal Detail:
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Title: Journal of neuroscience methods Volume: 187 ISSN: 1872-678X ISO Abbreviation: J. Neurosci. Methods Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-15 Completed Date: 2010-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905558 Medline TA: J Neurosci Methods Country: Netherlands |
Other Details:
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Languages: eng Pagination: 67-72 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Center for Integrative Neuroscience, University of T?bingen, T?bingen, Germany. fhaiss@pharma.uzh.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Action Potentials Animals Behavior Cerebral Cortex / physiology Electronics / instrumentation*, methods Evoked Potentials Head / surgery Hippocampus / physiology Mice Mice, Inbred C57BL Microelectrodes* Miniaturization Motor Activity / physiology Neurons / physiology Rats Rats, Long-Evans Restraint, Physical Wakefulness |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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