Document Detail

The mifepristone-misoprostol regimen for early medical abortion.
MedLine Citation:
PMID:  12112968     Owner:  NLM     Status:  MEDLINE    
The combination of mifepristone, an antiprogesterone known in the United States as Mifeprex (Danco Laboratories, New York, NY), and misoprostol, a prostaglandin analogue marketed in the United States under the brand name Cytotec (Pharmacia [formerly Searle], Peapack, NJ), provides a nonsurgical abortion in the early stages of a pregnancy. Mifepristone blocks the action of progesterone, a hormone necessary to sustain a pregnancy, whereas misoprostol causes contractions that expel the embryo and other pregnancy tissue. Since September 2000, mifepristone has been approved by the United States Food and Drug Administration for induced abortions of gestations of 49 days or less since the last menstrual period, but is not yet approved for any other uses. Misoprostol has long been approved to prevent and treat stomach ulcers.
C Ellertson; S N Waldman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current women's health reports     Volume:  1     ISSN:  1534-5874     ISO Abbreviation:  Curr Womens Health Rep     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2002-07-12     Completed Date:  2002-07-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  101120027     Medline TA:  Curr Womens Health Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  184-90     Citation Subset:  IM    
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MeSH Terms
Abortifacient Agents / administration & dosage*
Abortion, Induced / methods*
Administration, Intravaginal
Administration, Oral
Drug Therapy, Combination
Mifepristone / administration & dosage*
Misoprostol / administration & dosage*
Patient Satisfaction
Pregnancy Trimester, First
Self Administration
Reg. No./Substance:
0/Abortifacient Agents; 59122-46-2/Misoprostol; 84371-65-3/Mifepristone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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