Document Detail

A microfluidic mixer with grooves placed on the top and bottom of the channel.
MedLine Citation:
PMID:  15856089     Owner:  NLM     Status:  MEDLINE    
A new microfluidic mixer is presented consisting of a rectangular channel with grooves placed in the top and bottom. This not only increases the driving force behind the lateral flow, but allows for the formation of advection patterns that cannot be created with structures on the bottom alone. Chevrons, pointing in opposite directions on the top and bottom, are used to create a pair of vortices positioned side by side. Stripes running the width of the channel generate a pair of vertically stacked vortices. Computational fluid dynamics (CFD) simulations are used to model the behavior of the systems and provide velocity maps at cross-sections within the mixer. Experiments demonstrate the mixing that results when two segregated species enter the mixer side-by-side and pass through two cycles of the mixer (i.e., two alternating sets of four stripes and four chevrons).
Peter B Howell; David R Mott; Stephanie Fertig; Carolyn R Kaplan; Joel P Golden; Elaine S Oran; Frances S Ligler
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2005-04-13
Journal Detail:
Title:  Lab on a chip     Volume:  5     ISSN:  1473-0197     ISO Abbreviation:  Lab Chip     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-04-27     Completed Date:  2005-07-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  England    
Other Details:
Languages:  eng     Pagination:  524-30     Citation Subset:  IM    
Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington DC, 20375-5348, USA.
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MeSH Terms
Computer Simulation
Microfluidic Analytical Techniques / instrumentation,  methods
Microfluidics / instrumentation*,  methods*
Polymethyl Methacrylate / chemistry
Sensitivity and Specificity
Surface Properties
Reg. No./Substance:
9011-14-7/Polymethyl Methacrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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