Document Detail


The microcirculation and essential hypertension.
MedLine Citation:
PMID:  1791878     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Essential hypertension is characterized by a progressive increase of the mean arterial pressure paralleled by a concomitant increase in the total peripheral resistance. This elevated resistance is the consequence of (a) a decreased internal diameter, (b) an increased wall-to-lumen ratio or (c) a decreased number of small arteries or arterioles. A considerable part of the elevated vascular resistance is determined at the microcirculatory level. This paper reviews the studies performed to unravel the resistance-elevating mechanisms in the microvasculature of different tissues. Furthermore the possible role of the microcirculation in the pathogenesis of essential hypertension is discussed.
Authors:
P Draaijer; J L Le Noble; K M Leunissen; H A Struyker-Boudier
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Netherlands journal of medicine     Volume:  39     ISSN:  0300-2977     ISO Abbreviation:  Neth J Med     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-03-30     Completed Date:  1992-03-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0356133     Medline TA:  Neth J Med     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  158-69     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Animals
Humans
Hypertension / etiology*
Microcirculation / physiopathology*
Vascular Resistance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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