Document Detail


A method for the study of the dynamics of atherosclerotic involvement of human coronary arteries.
MedLine Citation:
PMID:  6740184     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A method able to reveal the progression of atherosclerosis from children to mature adults is proposed, based on the successive light microscopic examination of similar selected topographic sites of the coronary arterial tree placed in sequence according to age, sex and branching anatomical pattern. The dynamic reconstruction of thousands of static views revealed a linear and parallel increase in the number of all types of early atherosclerotic lesions: fibromuscular plaques, intimal necrotic areas, incorporated microthrombi and fatty streaks. Some endogenous and exogeneous risk factors for coronary heart disease accelerated this age-related rate of progression and also gave rise to particular cycles of evolution toward lesions of possible clinical significance.
Authors:
C Velican; D Velican
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Médecine interne     Volume:  22     ISSN:  0377-1202     ISO Abbreviation:  Med Interne     Publication Date:    1984 Apr-Jun
Date Detail:
Created Date:  1984-07-27     Completed Date:  1984-07-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7506353     Medline TA:  Med Interne     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Arteriosclerosis / pathology*
Child
Child, Preschool
Coronary Disease / pathology*
Coronary Vessels / pathology
Female
Humans
Infant
Male
Microscopy
Middle Aged
Thrombosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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