Document Detail


A method for directly establishing short-term cultures of human gestational choriocarcinoma in vitro.
MedLine Citation:
PMID:  6478446     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A procedure is described which offers a method for establishing, without recourse to a serial passage within animal hosts, short-term cultures of human gestational choriocarcinoma in vitro. The method involves the use of either post mortem or surgical biopsy tissue from patients with known choriocarcinomas. The tissues are subsequently sectioned on a freezing microtome and viable tumour selected for explantation in vitro. Radioimmuno assays of culture media supernatant confirm the trophoblastic nature of the cells growing in vitro, cytogenetic analyses of these cultures reveal several aneuploid modes.
Authors:
E B Ilgren; W B Jones
Related Documents :
8556516 - Production of interferons in human placental trophoblast subpopulations and their possi...
8838236 - Signal for term parturition is of trophoblast and therefore of fetal origin.
12029486 - Serum-dependent effects of igf-i and insulin on proliferation and invasion of human fir...
11550266 - Control of trophectoderm differentiation by inner cell mass-derived fibroblast growth f...
20554786 - Everolimus as a new potential antiproliferative agent in aggressive human bronchial car...
22042666 - Managing two cultural identities: the malleability of bicultural identity integration a...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer letters     Volume:  24     ISSN:  0304-3835     ISO Abbreviation:  Cancer Lett.     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-11-16     Completed Date:  1984-11-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600053     Medline TA:  Cancer Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  187-92     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cells, Cultured
Choriocarcinoma / genetics,  pathology*
Chorionic Gonadotropin / analysis
Culture Techniques / methods
Female
Humans
Karyotyping
Pregnancy
Radioimmunoassay
Uterine Neoplasms / genetics,  pathology*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A sensitive and specific radioimmunoassay for 1-beta-D-arabino-furanosylcytosine.
Next Document:  Carcinogenic activity of acrylamide in the skin and lung of Swiss-ICR mice.