Document Detail


A method for content uniformity determination of atenolol and losartan potassium in combined tablet dosage form.
MedLine Citation:
PMID:  21969756     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A simple, accurate, rapid, specific and reproducible UV spectrophotometric method was developed for estimation of content uniformity of atenolol and losartan potassium in its combined tablet dosage form. The method involves formation and solving the simultaneous equation using 226.4 and 254 nm as two wavelengths for atenolol and losartan, respectively. Developed method was employed to determine the atenolol and losartan content in ten individual tablet units of five market formulations. Methanol was used as solvent. The method was validated. From the results, it was concluded that all brands are within the content uniformity limit, 85-115%.
Authors:
S A Shah; R B Vyas; B A Vyas; N R Maniyar; R S Chauhan; D R Shah
Related Documents :
21726876 - Capillary electrophoresis with led-induced native fluorescence detection for determinat...
21644646 - A device for sampling and determination of total particulate mercury in ambient air.
11874006 - Effect of serial extraction alone on crowding: relationship between closure of residual...
14521316 - Direct extraction of alkylphenols, chlorophenols and bisphenol a from acid-digested sed...
22732386 - Characterization of multiple prompt gamma-ray analysis (mpga) system at jaea for elemen...
14717376 - Comparison of the mouse bioassay and enzyme-linked immunosorbent assay procedures for t...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of pharmaceutical sciences     Volume:  72     ISSN:  1998-3743     ISO Abbreviation:  Indian J Pharm Sci     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2011-10-04     Completed Date:  2011-11-10     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  7809431     Medline TA:  Indian J Pharm Sci     Country:  India    
Other Details:
Languages:  eng     Pagination:  792-4     Citation Subset:  -    
Affiliation:
Department of Quality Assurance, Maliba Pharmacy College, Gopal Vidyanagar, Bardoli-Mahuva Road, Tarsadi 394 350, Dist. Surat, Gujarat, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prospective observational evaluation of incidences and implications of drug-drug interactions induce...
Next Document:  Antioxidant Effect of Tinospora cordifolia Extract in Alloxan-induced Diabetic Rats.