Document Detail


A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis: preliminary results.
MedLine Citation:
PMID:  23025771     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objective: The aim of the present study was to investigate the metabolic profile of preterm human breast milk (HBM) by using a metabolomic approach. Methods: NMR spectroscopy and GC/MS were used to analyze the water-soluble and lipid fractions extracted from milk samples obtained from mothers giving birth at 26-36 weeks of gestation. For the sake of comparison, preterm formula milk was also studied. Results: The multivariate statistical analysis of the data evidenced biochemical variability both between preterm HBM and commercial milk and within the group of HBM samples. Conclusions: The preliminary results of this study suggest that metabolomics may provide a promising tool to study aspects related to the nutrition and health of preterm infant.
Authors:
Flaminia Cesare Marincola; Antonio Noto; Pierluigi Caboni; Alessandra Reali; Luigi Barberini; Milena Lussu; Federica Murgia; Maria Laura Santoru; Luigi Atzori; Vassilios Fanos
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  25     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  62-7     Citation Subset:  IM    
Affiliation:
Department of Chemical and Geological Science, University of Cagliari , Cagliari , Italy.
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