Document Detail


The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens.
MedLine Citation:
PMID:  690978     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The metabolism and motility of human ejaculated spermatozoa incubated in vitro with steroids were studied. Progesterone and norethynodrel depressed the respiration, glycolytic metabolism and the motility of washed spermatozoa. Lynoestrenol did not affect the respiration or glycolysis of the spermatozoa, but did inhibit motility. Oestradiol did not cause any consistent alteration of the sperm metabolism, and did not affect the motility. Progesterone and norethynodrel appeared to act on the plasma membrane of human spermatozoa to increase its permeability and hence to facilitate the loss of essential cofactors required for the glycolytic and oxidative processes.
Authors:
R V Hyne; R N Murdoch; B Boettcher
Related Documents :
24804148 - Assessing the effectiveness of tuberculosis management in brushtail possums (trichosuru...
23217158 - Prevalence of porcine cysticercosis and associated risk factors in homa bay district, k...
3233508 - Predicting the fertilising ability of avian semen: the development of an objective colo...
18494578 - Ecdysone metabolism in diapause eggs and non-diapause eggs of the silkworm, bombyx mori.
23594708 - Adverse metabolic effects of dietary fructose: results from the recent epidemiological,...
23470418 - Bioactivation of bisphenol a and its analogs (bpf, bpaf, bpz and dmbpa) in human liver ...
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  53     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-11-18     Completed Date:  1978-11-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  315-22     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Energy Metabolism / drug effects
Estradiol / pharmacology*
Humans
Lynestrenol / pharmacology*
Male
Norethynodrel / pharmacology*
Progesterone / pharmacology*
Sperm Motility / drug effects*
Spermatozoa / drug effects,  metabolism*
Chemical
Reg. No./Substance:
50-28-2/Estradiol; 52-76-6/Lynestrenol; 57-83-0/Progesterone; 68-23-5/Norethynodrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of a progesterone-releasing intravaginal device on the milk progesterone levels, vaginal flor...
Next Document:  Luteotrophic effect of the rabbit blastocyst.