| The metabolism and motility of human spermatozoa in the presence of steroid hormones and synthetic progestagens. | |
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MedLine Citation:
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PMID: 690978 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The metabolism and motility of human ejaculated spermatozoa incubated in vitro with steroids were studied. Progesterone and norethynodrel depressed the respiration, glycolytic metabolism and the motility of washed spermatozoa. Lynoestrenol did not affect the respiration or glycolysis of the spermatozoa, but did inhibit motility. Oestradiol did not cause any consistent alteration of the sperm metabolism, and did not affect the motility. Progesterone and norethynodrel appeared to act on the plasma membrane of human spermatozoa to increase its permeability and hence to facilitate the loss of essential cofactors required for the glycolytic and oxidative processes. |
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Authors:
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R V Hyne; R N Murdoch; B Boettcher |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: Journal of reproduction and fertility Volume: 53 ISSN: 0022-4251 ISO Abbreviation: J. Reprod. Fertil. Publication Date: 1978 Jul |
Date Detail:
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Created Date: 1978-11-18 Completed Date: 1978-11-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376367 Medline TA: J Reprod Fertil Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 315-22 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Energy Metabolism
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drug effects Estradiol / pharmacology* Humans Lynestrenol / pharmacology* Male Norethynodrel / pharmacology* Progesterone / pharmacology* Sperm Motility / drug effects* Spermatozoa / drug effects, metabolism* |
| Chemical | |
Reg. No./Substance:
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50-28-2/Estradiol; 52-76-6/Lynestrenol; 57-83-0/Progesterone; 68-23-5/Norethynodrel |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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