| The metabolic fate of [3H]estradiol in relation to dietary intake of boron in ovariectomized rats. | |
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MedLine Citation:
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PMID: 8518209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It has been reported that boron (B) deprivation reversibly lowers plasma estradiol levels in postmenopausal women. In order to establish whether this reflects disturbances in the estrogen catabolic pathway and in particular in catechol estrogen metabolism, the influence of dietary B on the catabolism of [3H]estradiol-17 beta has been studied in ovariectomized rats. Rats were given diets containing < 0.1 or 40 mg B.kg-1, ovariectomized and then infused with [3H]estradiol-17 beta using osmotic pumps. Analysis of urine samples for conjugated, catechol and non-catechol estrogens did not reveal any effects of B on the recovery or the metabolic fate of tritium from the infused estradiol. These results do not therefore support the proposal that B influences estrogen catabolism by interacting with catechol estrogens. |
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Authors:
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J H Beattie |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of steroid biochemistry and molecular biology Volume: 45 ISSN: 0960-0760 ISO Abbreviation: J. Steroid Biochem. Mol. Biol. Publication Date: 1993 Jun |
Date Detail:
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Created Date: 1993-07-27 Completed Date: 1993-07-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9015483 Medline TA: J Steroid Biochem Mol Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 549-54 Citation Subset: IM |
Affiliation:
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Division of Biochemical Sciences, Rowett Research Institute, Bucksburn, Aberdeen, Scotland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Boron / pharmacology* Diet* Estradiol / metabolism* Estrogens / urine Female Ovariectomy* Rats Tritium |
| Chemical | |
Reg. No./Substance:
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0/Estrogens; 10028-17-8/Tritium; 50-28-2/Estradiol; 7440-42-8/Boron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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