| A metabolic approach to the evaluation of peripheral vascular disease. | |
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MedLine Citation:
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PMID: 12579 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-five patients with occlusive disease of the arteries underwent metabolic studies. The arteriovenous differences of lactate, glucose and oxygen varied with the severity of the ischemic process, as assessed clinically. Lactate release and glucose extraction were significantly different from control values of patients with rest pain or with ischemic gangrene, while values in patients with claudication were comparable with those in the control group. Percutaneous muscle surface pH measurements, which reflect lactate release, decreased directly with diminished perfusion. Metabolic assessment of arterial occlusive disease may prove to be a useful clinical approach. |
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Authors:
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T F O'Donnel; G H Clowes; N L Browse; N T Ryan; G L Blackburn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Surgery, gynecology & obstetrics Volume: 144 ISSN: 0039-6087 ISO Abbreviation: Surg Gynecol Obstet Publication Date: 1977 Jan |
Date Detail:
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Created Date: 1977-02-26 Completed Date: 1977-02-26 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0101370 Medline TA: Surg Gynecol Obstet Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 51-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Arterial Occlusive Diseases / metabolism* Female Gangrene / metabolism Glucose / metabolism Humans Hydrogen-Ion Concentration Ischemia / metabolism Lactates / metabolism Leg / blood supply* Male Middle Aged Muscles / metabolism* Oxygen Consumption |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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