| A meta-analysis of the relationship between endometrial thickness and outcome of in vitro fertilization cycles. | |
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MedLine Citation:
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PMID: 22346080 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: The objective was to evaluate the relationship between endometrial thickness on the day of human chorionic gonadotropin administration and pregnancy outcome in in vitro fertilization cycles. DESIGN: This was a systematic review and meta-analysis. MATERIALS AND METHODS: We identified 484 articles using Cochrane library, PubMed, Web of Science, and Embase searches with various key words including endometrial thickness, pregnancy, assisted reproductive technology, endometrial pattern, and in vitro fertilization. A total of 14 studies with data on endometrial thickness and outcome were selected, representing 4922 cycles (2204 pregnant and 2718 nonpregnant). The meta-analysis with a random effects model was performed using comprehensive meta-analysis software. We calculated the standardized mean difference, odds ratio (OR), and 95% confidence intervals (CIs). RESULTS: There was a significant difference in the mean endometrial thickness between pregnant and nonpregnant groups (P<0.001), with a standardized mean difference of 0.4 mm (95% CI 0.22-0.58). The OR for pregnancy was 1.40 (95% CI 1.24-1.58). CONCLUSIONS: The mean endometrial thickness was significantly higher in pregnant women compared to nonpregnant. The mean difference between two groups was <1 mm which may not be clinically meaningful. Although there may be a relationship between endometrial thickness and pregnancy, implantation potential is probably more complex than a single ultrasound measurement can determine. |
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Authors:
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Mazdak Momeni; Mohammad H Rahbar; Ertug Kovanci |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of human reproductive sciences Volume: 4 ISSN: 1998-4766 ISO Abbreviation: J Hum Reprod Sci Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2012-02-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101473512 Medline TA: J Hum Reprod Sci Country: India |
Other Details:
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Languages: eng Pagination: 130-7 Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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