| A membrane-associated autoantibody in a case of myasthenia gravis with chronic hepatitis. | |
| | |
MedLine Citation:
|
PMID: 786517 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A new antibody reacting with a cell membrane-related antigen is described in a patient with myasthenia gravis and chronic liver disease. The antibody gave a striking peripheral immunofluorescence in all cells tested and did not react with smooth muscle fibres, being distinct from anti-actin and anti-myosin antibodies. The antigen was widely distributed in human and animal tissues. The exact relationship of this antibody to the clinical condition is not obvious but its presence is further evidence of widespread disturbances of humoral immunity in myasthenia gravis. |
| | |
Authors:
|
A J Fairfax; D Doniach; C E Wells |
Related Documents
:
|
1718457 - The main immunogenic region of the acetylcholine receptor. structure and role in myasth... 1472127 - Interactions of synovial fluid immunoglobulins with chondrocytes. 20820197 - Periodontitis in ra-the citrullinated enolase connection. 7678427 - Multiclonal synovial t cell response to yersinia enterocolitica in reactive arthritis: ... 7532427 - Cytotoxic t lymphocytes induced by liposomal antigens: mechanisms of immunological pres... 3081727 - Characterisation of mouse monoclonal antibodies produced by immunisation with a single ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical and experimental immunology Volume: 25 ISSN: 0009-9104 ISO Abbreviation: Clin. Exp. Immunol. Publication Date: 1976 Sep |
Date Detail:
|
Created Date: 1976-11-21 Completed Date: 1976-11-21 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 0057202 Medline TA: Clin Exp Immunol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 383-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Autoantibodies
/
analysis* Cell Membrane / immunology* Chronic Disease Female Fluorescent Antibody Technique Hepatitis / complications* Humans Immunoglobulin G Middle Aged Muscle, Smooth / immunology Myasthenia Gravis / complications, immunology* |
| Chemical | |
Reg. No./Substance:
|
0/Autoantibodies; 0/Immunoglobulin G |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Autosomal reciprocal translocations and 13/14 translocations: a population study.
Next Document: Liver cell surface localization of hepatitis B antigen and of immunoglobulins in acute and chronic h...