| Sex/gender medicine. The biological basis for personalized care in cardiovascular medicine. | |
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MedLine Citation:
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PMID: 19729858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sex differences in morbidity and mortality associated with cardiovascular disease have been recognized by the medical community for decades. Investigation into the underlying biological basis of these differences was largely neglected by the scientific community until a report released by the Institute of Medicine in the United States in 2001 "Exploring the Biological Contributions to Human Health: Does Sex Matter?" Recommendations from this report included the need for more accurate use of the terms "sex" and "gender", better tools and resources to study the biological basis of sex differences, integration of findings from different levels of biological organization and continued synergy between basic and clinical researchers. Ten years after the Institute's report, this review evaluates some of the sex differences in cardiovascular disease, reviews new approaches to study sex differences and emphasizes areas where further research is required. In the era of personalized medicine, the study of the biological basis of sex differences promises to optimize preventive, diagnostic and therapeutic strategies for cardiovascular disease in men and women, but will require diligence by the scientific and medical communities to remember that sex does matter. |
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Authors:
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Faisal A Arain; Fatima H Kuniyoshi; Ahmed D Abdalrhim; Virginia M Miller |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2009-09-04 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 73 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-25 Completed Date: 2009-12-07 Revised Date: 2011-05-13 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 1774-82 Citation Subset: IM |
Affiliation:
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Department of General Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Atherosclerosis
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diagnosis,
etiology,
therapy Autonomic Nervous System / physiopathology Biomedical Research Cardiovascular Diseases* / diagnosis, etiology, therapy Female Heart Failure / diagnosis, etiology, therapy Humans Hypertension / diagnosis, etiology, therapy Individualized Medicine* Male Patient Selection* Risk Assessment Risk Factors Sex Characteristics Sex Factors |
| Grant Support | |
ID/Acronym/Agency:
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1 KL2 RR024151/RR/NCRR NIH HHS; KL2 RR024151-01/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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