| The medical risks of obesity. | |
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MedLine Citation:
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PMID: 19940414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Obesity is at epidemic proportions in the United States and in other developed and developing countries. The prevalence of obesity is increasing not only in adults, but especially among children and adolescents. In the United States in 2003 to 2004, 17.1% of children and adolescents were overweight, and 32.2% of adults were obese. Obesity is a significant risk factor for and contributor to increased morbidity and mortality, most importantly from cardiovascular disease (CVD) and diabetes, but also from cancer and chronic diseases, including osteoarthritis, liver and kidney disease, sleep apnea, and depression. The prevalence of obesity has increased steadily over the past 5 decades, and obesity may have a significant impact on quality-adjusted life years. Obesity is also strongly associated with an increased risk of all-cause mortality as well as cardiovascular and cancer mortality. Despite the substantial effects of obesity, weight loss can result in a significant reduction in risk for the majority of these comorbid conditions. Those comorbidities most closely linked to obesity must be identified to increase awareness of potential adverse outcomes. This will allow health care professionals to identify and implement appropriate interventions to reduce patient risk and mortality. A systematic search strategy was used to identify published literature between 1995 and 2008 that reported data from prospective longitudinal studies of obesity and comorbid medical conditions. This article will review evidence for significant associations of obesity with comorbidities to provide information useful for optimal patient management. |
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Authors:
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Xavier Pi-Sunyer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Postgraduate medicine Volume: 121 ISSN: 1941-9260 ISO Abbreviation: Postgrad Med Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-26 Completed Date: 2010-01-08 Revised Date: 2011-05-10 |
Medline Journal Info:
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Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: United States |
Other Details:
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Languages: eng Pagination: 21-33 Citation Subset: AIM; IM |
Affiliation:
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Division of Endocrinology Diabetes and Nutrition, St. Luke's-Roosevelt Hospital Center, New York, NY 10025, USA. fxp1@columbia.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiovascular Diseases
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epidemiology*,
etiology* Comorbidity Diabetes Mellitus / epidemiology, etiology Humans Mortality Neoplasms / epidemiology*, etiology* Obesity / complications*, epidemiology*, prevention & control Risk United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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P30 DK026687-29/DK/NIDDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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