Document Detail


The medical management of epilepsy.
MedLine Citation:
PMID:  22146419     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
With many new medications on the market and new data about the various side-effects of antiepilepsy drugs (AEDs), the medical management of epilepsy can seem unnecessarily complicated for the non-specialist. The process can be thought of taking place in 7 steps: 1) assessing the need for medications; 2) defining the seizures and classifying the epilepsy syndrome; 3) knowing which medications are best used in which syndromes; 4) taking into account patient priorities when choosing a medication, such as cotreatment or avoidance of neurobehavioral issues and weight loss or gain; 5) considering other life issues, such as planning a pregnancy and breastfeeding; 6) choosing a maintenance dose and deciding when to consider a change to another medication or to use dual therapy; and 7) if seizure-free, which patients to consider AED reduction or withdrawal. The goal is simply, no seizures and no side-effects. Seizure freedom is an important goal to reduce injury, mortality and improve quality of life. Improving tolerability is equally as important, as both acute and chronic side-effects of AEDs can be as disabling as seizures themselves.
Authors:
D J Chong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Panminerva medica     Volume:  53     ISSN:  1827-1898     ISO Abbreviation:  Panminerva Med     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421110     Medline TA:  Panminerva Med     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  217-26     Citation Subset:  IM    
Affiliation:
Division of Epilepsy and Sleep, Department of Clinical Neurology, Columbia University Medical Center, New York, NY, USA - dc2223@columbia.edu.
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