Document Detail


The mechanisms of schizophrenia.
MedLine Citation:
PMID:  8038584     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Current investigations of the mechanisms of schizophrenia usually employ one of three possible explanatory models: a single disease entity model, a multiple disease entity model, and a dimensions of psychopathology model. None of these is at present preeminent. These models are used to explore four different types of mechanisms that may produce the symptoms of schizophrenia: neurodevelopmental, neural circuitry, genetic/molecular mechanisms, and chemical anatomy.
Authors:
N C Andreasen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Current opinion in neurobiology     Volume:  4     ISSN:  0959-4388     ISO Abbreviation:  Curr. Opin. Neurobiol.     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-08-23     Completed Date:  1994-08-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9111376     Medline TA:  Curr Opin Neurobiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  245-51     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242-1057.
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MeSH Terms
Descriptor/Qualifier:
Brain / growth & development
Dopamine / metabolism
Humans
Models, Neurological*
Neural Pathways / physiopathology
Schizophrenia / genetics,  metabolism,  physiopathology*
Schizophrenic Psychology*
Grant Support
ID/Acronym/Agency:
MHCRC 43271/MH/NIMH NIH HHS; NIMH MH31593/MH/NIMH NIH HHS; NIMH MH40856/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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