Document Detail


On the mechanisms of fatty acid transformations in membranes.
MedLine Citation:
PMID:  6796797     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane-bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process.
Authors:
M Gan-Elepano; E Aeberhard; J F Mead
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Lipids     Volume:  16     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1982-02-25     Completed Date:  1982-02-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  790-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Albumins / pharmacology
Animals
Arachidonic Acid
Arachidonic Acids / metabolism
Brain / metabolism*
Fatty Acids / metabolism*
Malonyl Coenzyme A / metabolism
Membrane Lipids / metabolism*
Microsomes / metabolism
Rats
Grant Support
ID/Acronym/Agency:
GM-K-6-A,177/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Albumins; 0/Arachidonic Acids; 0/Fatty Acids; 0/Membrane Lipids; 506-32-1/Arachidonic Acid; 524-14-1/Malonyl Coenzyme A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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