| The mechanism of palatal shelf elevation and the pathogenesis of cleft palate. | |
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MedLine Citation:
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PMID: 143115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Both normal Wistar rat fetuses and those with cleft palate induced by 5-Fluoro-2-Desoxyuridine were studied with a view to elucidating the mechanism of palatal shelf elevation and the pathogenesis of cleft palate. It was postulated that normal shelf elevation is brought about rapidly by an intrinsic turgor shelf force generated by binding of water to mucopolysaccharides. Interference with mucopolysaccharide synthesis would seem to be an important factor in the pathogenesis of some types of cleft palate. |
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Authors:
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M W Ferguson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Virchows Archiv. A, Pathological anatomy and histology Volume: 375 ISSN: 0340-1227 ISO Abbreviation: Virchows Arch A Pathol Anat Histol Publication Date: 1977 Aug |
Date Detail:
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Created Date: 1977-10-31 Completed Date: 1977-10-31 Revised Date: 2008-02-20 |
Medline Journal Info:
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Nlm Unique ID: 7505137 Medline TA: Virchows Arch A Pathol Anat Histol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 97-113 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cleft Palate / chemically induced, embryology* Female Floxuridine Glycosaminoglycans / biosynthesis Palate / embryology* Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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0/Glycosaminoglycans; 50-91-9/Floxuridine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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