Document Detail


A mechanism involved in the plaque enhancement effect of sodium thiosulfate for foot-and-mouth disease viruses.
MedLine Citation:
PMID:  1331716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A mechanism involved in the plaque enhancement effect of foot-and-mouth disease viruses (FMDV) by the addition of sodium thiosulfate (Hypo) in the agar overlay medium (AOM) previously reported was studied. It was experimentally proved that the diffusion of virus particles through agar overlay medium was enhanced when this salt was incorporated. Accordingly, the enlarged plaque formation was assumed to be caused by the enhanced diffusion of viral progenies produced in infectious centers during plaque assays.
Authors:
K Kadoi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Microbiologica     Volume:  15     ISSN:  0391-5352     ISO Abbreviation:  Microbiologica     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1992-12-15     Completed Date:  1992-12-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7902903     Medline TA:  Microbiologica     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  399-401     Citation Subset:  IM    
Affiliation:
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy.
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MeSH Terms
Descriptor/Qualifier:
Agar
Animals
Aphthovirus / drug effects*,  growth & development
Plaque Assay
Thiosulfates / pharmacology*
Chemical
Reg. No./Substance:
0/Thiosulfates; 7772-98-7/sodium thiosulfate; 9002-18-0/Agar

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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