Document Detail

The measurement of serum fibrinogen levels in patients with acute coronary syndrome.
MedLine Citation:
PMID:  17768458     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Serum fibrinogen level (SFL) is thought to be one of the risk factors for coronary artery disease (CAD). The purpose of this study was to measure the SFL in patients with acute coronary syndrome (ACS). METHODS: This study was performed in patients with ACS, admitted in Shahid Beheshti Hospital, Babol, Iran, from February 2005 to June 2006. Two hundred patients with ACS were divided into 4 groups: Group I - ST elevated myocardial infarction (STEMI); Group II - non-ST elevated myocardial infarction (NSTEMI); Group III - unstable angina (U/A) with ST-T change; and Group IV - U/A without ST-T change. Each group includes 50 patients. Twenty-four hours after admission, the SFL was measured using chromatography methods. The data were collected and analyzed. RESULTS: The mean SFL per mg/dl in each group are: Group I - 377.8 +/- 28, Group II - 417.2 +/- 26.8, Group III - 335.4 +/- 19.8, and Group IV - 305.1 +/- 13.8. The SFL in Group II was significantly higher than the other groups (p=0.002). The SFL in Group II was higher than in Group III (p=0.02), and much higher than in Group IV (p=0.000). The SFL in Group III was more than in Group IV (p=0.018). CONCLUSION: The results show that SFL is an important marker in patients with ACS, with ST-T change.
Mohammad T Omran; Simin Asadollahi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  28     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-04     Completed Date:  2008-02-05     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  1350-2     Citation Subset:  IM    
Department of Cardiology, Shahid Beheshti Hospital, Babol Medical University, Babol, Iran.
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MeSH Terms
Acute Coronary Syndrome / blood*,  complications,  physiopathology*
Angina, Unstable / blood*,  complications,  physiopathology*
Case-Control Studies
Fibrinogen / metabolism*
Middle Aged
Reg. No./Substance:

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