Document Detail


Is the measurement of inferior thyroid artery blood flow velocity by color-flow Doppler ultrasonography useful for differential diagnosis between gestational transient thyrotoxicosis and Graves' disease? A prospective study.
MedLine Citation:
PMID:  22358236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the role of peak systolic velocity, end-diastolic velocity and resistance indices of both the right and left inferior thyroid arteries measured by color-flow Doppler ultrasonography for a differential diagnosis between gestational transient thyrotoxicosis and Graves' disease during pregnancy.
METHODS: The right and left inferior thyroid artery-peak systolic velocity, end-diastolic velocity and resistance indices of 96 patients with thyrotoxicosis (41 with gestational transient thyrotoxicosis, 31 age-matched pregnant patients with Graves' disease and 24 age- and sex-matched non-pregnant patients with Graves' disease) and 25 age and sex-matched healthy euthyroid subjects were assessed with color-flow Doppler ultrasonography.
RESULTS: The right and left inferior thyroid artery-peak systolic and end-diastolic velocities in patients with gestational transient thyrotoxicosis were found to be significantly lower than those of pregnant patients with Graves' disease and higher than those of healthy euthyroid subjects. However, the right and left inferior thyroid artery peak systolic and end-diastolic velocities in pregnant patients with Graves' disease were significantly lower than those of non-pregnant patients with Graves' disease. The right and left inferior thyroid artery peak systolic and end-diastolic velocities were positively correlated with TSH-receptor antibody levels. We found an overlap between the inferior thyroid artery-blood flow velocities in a considerable number of patients with gestational transient thyrotoxicosis and pregnant patients with Graves' disease.
CONCLUSIONS: This study suggests that the measurement of inferior thyroid artery-blood flow velocities with color-flow Doppler ultrasonography does not have sufficient sensitivity and specificity to be recommended as an initial diagnostic test for a differential diagnosis between gestational transient thyrotoxicosis and Graves' disease during pregnancy.
Authors:
Sayid Shafi Zuhur; Alper Ozel; Selvinaz Velet; Mehmet Sait Buğdacı; Esra Cil; Yüksel Altuntas
Related Documents :
22682136 - Pl-11 transfusion issues in cancer patients.
22687616 - Nitric oxide formation versus scavenging: the red blood cell balancing act.
9548776 - Computational fluid dynamics model for predicting flow of viscous fluids in a large fer...
1000846 - An improved assay of thyrotropin in dried blood samples on filter paper as a screening ...
22840456 - Combined apach | score and arterial blood lactate clearance rate to predict the prognos...
2668146 - Increased galactose clearance after liver transplantation: a measure of increased blood...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics (São Paulo, Brazil)     Volume:  67     ISSN:  1980-5322     ISO Abbreviation:  Clinics (Sao Paulo)     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-23     Completed Date:  2012-11-08     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101244734     Medline TA:  Clinics (Sao Paulo)     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Affiliation:
Sisli Etfal Training and Research Hospital, Endocrinology and Metabolism Clinic, Istanbul, Turkey. zuhur744@gmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Arteries / ultrasonography
Blood Flow Velocity / physiology
Diagnosis, Differential
Epidemiologic Methods
Female
Graves Disease / physiopathology,  ultrasonography*
Humans
Pregnancy
Pregnancy Complications / physiopathology,  ultrasonography*
Thyroid Gland / blood supply*,  ultrasonography
Thyrotoxicosis / physiopathology,  ultrasonography*
Ultrasonography, Doppler, Color*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Establishment of the bacterial fecal community during the first month of life in Brazilian newborns.
Next Document:  Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysi...