| The measurement of hypoxanthine, xanthine, inosine and uridine in umbilical cord blood and fetal scalp blood samples as a measure of fetal hypoxia. | |
| | |
MedLine Citation:
|
PMID: 7225296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Hypoxanthine, xanthine, inosine, urate and uridine, were measured in 149 samples of umbilical cord plasma using high pressure liquid chromatography. In spite of a good correlation with the simpler oxygen consumption method for measuring hypoxanthine, there was no clear discrimination between hypoxic and well oxygenated infants, although mean concentrations were higher in infants with well defined criteria of intrapartum hypoxia or bith asphyxia, there was overlap with the normal range. Fetal scalp blood samples were also found to be clinically unhelpful in the diagnosis of intrapartum hypoxia, at least in part due to variable degrees of haemolysis in the specimens. There were poor correlations between hypoxanthine concentrations and those of hydrogen ion, base deficit and lactate. Uridine concentrations were significantly higher in arterial cord blood than in venous cord blood but hypoxanthine or xanthine concentrations did not show this difference. |
| | |
Authors:
|
M C O'Connor; R A Harkness; R J Simmonds; F E Hytten |
Related Documents
:
|
19646176 - Pregnant women's knowledge and attitudes about stem cells and cord blood banking. 17624896 - Is mechanical deformation of the suboccipital vertebral artery during cervical spine ro... 3889816 - Opsonic activity of cord blood sera against various species of microorganism. 10482286 - An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in... 15601066 - Experimental studies of pattern formation in a reaction-advection-diffusion system. 1830036 - Contribution of leg vascular tissues to the overall metabolic clearance of human atrial... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: British journal of obstetrics and gynaecology Volume: 88 ISSN: 0306-5456 ISO Abbreviation: Br J Obstet Gynaecol Publication Date: 1981 Apr |
Date Detail:
|
Created Date: 1981-07-23 Completed Date: 1981-07-23 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7503752 Medline TA: Br J Obstet Gynaecol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 381-90 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Fetal Blood / analysis* Fetal Hypoxia / diagnosis* Humans Hypoxanthines / blood* Infant, Newborn Inosine / blood* Pregnancy Scalp / blood supply, embryology Uric Acid / blood Uridine / blood* Xanthines / blood* |
| Chemical | |
Reg. No./Substance:
|
0/Hypoxanthines; 0/Xanthines; 58-63-9/Inosine; 58-96-8/Uridine; 69-93-2/Uric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Raised hypoxanthine, xanthine and uridine concentrations in meconium stained amniotic fluid and duri...
Next Document: Reliability of ultrasound as compared to direct fetal electrocardiography for antepartum cardiotocog...