| The measurement of exhaled nitric oxide in routine practice. | |
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MedLine Citation:
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PMID: 20101925 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Exhaled nitric oxide (NO) is considered the most easily available clinical test to indirectly assess the level of eosinophilic airway inflammation in asthma, and to predict the efficacy of anti-inflammatory treatment with inhaled corticosteroids (ICS). It is possible to measure the level of exhaled NO using online or offline methods. The most widely used online method employs techniques that enable NO in exhaled air to be measured in a single exhalation, calculating the value at the end-expiratory plateau. Because of the correlation between the level of exhaled NO with the level of eosinophilic inflammation in the airway of asthmatic patients, it has been proposed as a clinical marker in the practice of respiratory and allergy physicians with differing targets. In particular it is considered to be highly effective in the diagnosis of allergic asthma, to be capable of identifying those patients with a higher response probability to inhaled corticosteroids, and to a lesser extent, to be of value in contributing to the management of the disease. The possibility of easily taking measurements of FeNO in an office setting even by relatively young children, and the availability of a portable device, opens a significant perspective for the routine use of FeNO evaluation in daily practice. |
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Authors:
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G Paiola; L Tenero; G Piacentini |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: European annals of allergy and clinical immunology Volume: 41 ISSN: 1764-1489 ISO Abbreviation: Eur Ann Allergy Clin Immunol Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2010-01-27 Completed Date: 2010-09-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101466614 Medline TA: Eur Ann Allergy Clin Immunol Country: Italy |
Other Details:
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Languages: eng Pagination: 131-5 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, University of Verona, Verona, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use Anti-Inflammatory Agents / therapeutic use Asthma / diagnosis*, drug therapy, pathology, physiopathology Biological Markers / analysis* Diagnostic Tests, Routine / methods* Eosinophils / pathology Exhalation Humans Nitric Oxide / analysis* Practice Guidelines as Topic Prognosis Respiratory System / metabolism*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents; 0/Biological Markers; 10102-43-9/Nitric Oxide |
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