| Is maximal acid output useful in identifying relapsing duodenal ulcer patients? | |
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MedLine Citation:
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PMID: 3840819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a group of 94 duodenal ulcer patients consecutively studied and followed-up for 1 year, subjects with maximal acid output (M.A.O.) above 60 mmol/hour (mostly heavy-smoking men), were found to relapse more frequently than those with lower M.A.O. values (72.2% versus 27.6%; p less than 0.0005). A significantly higher relapse rate was also detected in patients treated with maintenance dosages of effective antisecretory drugs (cimetidine, ranitidine, pirenzepine) and presenting M.A.O. over 60 mmol/hour. It is yet to be established whether an alternative therapeutic regime may prove effective in preventing ulcer recurrence in patients with gastric hypersecretion. |
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Authors:
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G Battaglia; R Farini; F Di Mario; F Vianello; A Piccoli; M Plebani; R Naccarato |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical gastroenterology Volume: 7 ISSN: 0192-0790 ISO Abbreviation: J. Clin. Gastroenterol. Publication Date: 1985 Oct |
Date Detail:
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Created Date: 1986-01-16 Completed Date: 1986-01-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7910017 Medline TA: J Clin Gastroenterol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 375-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Benzodiazepinones / therapeutic use Cimetidine / therapeutic use Duodenal Ulcer / diagnosis* Female Follow-Up Studies Gastric Acid / secretion* Humans Male Middle Aged Pirenzepine Ranitidine / therapeutic use Recurrence Smoking |
| Chemical | |
Reg. No./Substance:
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0/Benzodiazepinones; 28797-61-7/Pirenzepine; 51481-61-9/Cimetidine; 66357-35-5/Ranitidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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