Document Detail


A mathematical model of the human menstrual cycle.
MedLine Citation:
PMID:  5132945     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A mathematical model for the hormonal interactions of the human menstrual cycle is presented. The feedback effects of estrogen on the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are considered, including a mechanism describing the midcycle LH peak. Computer simulation with this model yields results which are periodic and in good agreement with physiological data.
Authors:
W J Shack; P Y Tam; T J Lardner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biophysical journal     Volume:  11     ISSN:  0006-3495     ISO Abbreviation:  Biophys. J.     Publication Date:  1971 Oct 
Date Detail:
Created Date:  1972-03-09     Completed Date:  1972-03-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370626     Medline TA:  Biophys J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  835-48     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Computers
Corpus Luteum / secretion
Estradiol / blood
Estrogens
Feedback
Female
Follicle Stimulating Hormone / blood,  secretion
Humans
Kinetics
Luteinizing Hormone / blood,  secretion
Mathematics
Menstruation*
Models, Biological
Ovarian Follicle / growth & development
Ovulation
Periodicity
Pituitary Gland
Progesterone / blood,  secretion
Chemical
Reg. No./Substance:
0/Estrogens; 50-28-2/Estradiol; 57-83-0/Progesterone; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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