Document Detail

A mathematical model of the cardiovascular response to +Gz acceleration.
MedLine Citation:
PMID:  11537428     Owner:  NASA     Status:  MEDLINE    
The cardiovascular system is the limiting factor for human tolerance to positive Gz (head-to-foot) acceleration induced during maneuvers of fighter aircrafts. Safe handling of modern fighter aircrafts with higher acceleration capabilities require the use of countermeasures such as a G-suit or breathing at a positive pressure. A better understanding of the mechanisms involved in the cardiovascular response to +Gz acceleration would help improve the design and application of protective measures. This paper presents a simple mathematical model of the cardiovascular system which incorporates arterial and cardiopulmonary baroreflexes, left ventricular-peripheral circulation interaction and decreased venous return. This model is capable of reproducing observed overall cardiovascular response to +Gz acceleration.
F M Melchior; R S Srinivasan; G Ossard; Clère J-M
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Physiologist     Volume:  36     ISSN:  0031-9376     ISO Abbreviation:  Physiologist     Publication Date:  1993  
Date Detail:
Created Date:  1995-06-16     Completed Date:  1995-06-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401143     Medline TA:  Physiologist     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S62-3     Citation Subset:  S    
Laboratoire de Médecine Aérospatiale, Centre d'Essais en Vol, Brétigny, France.
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MeSH Terms
Baroreflex / physiology*
Blood Pressure
Hemodynamics / physiology*
Models, Cardiovascular*
Stroke Volume / physiology
Ventricular Function, Left / physiology*
R S Srinivasan / Krug Life Sciences, Houston, TX

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