| A mathematical formula to estimate in vivo thyroid volume from two-dimensional ultrasonography. | |
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MedLine Citation:
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PMID: 18651825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The determination of thyroid volume (TV) is required for the management of thyroid diseases. Since two-dimensional ultrasonography (2D-US) has become the accepted method for the assessment of TV (2D-US-TV), we verified whether it accurately assesses postsurgical measured TV (PS-TV). METHODS: In 92 patients who underwent total thyroidectomy by conventional cervicotomy, 2D-US-TV obtained by the ellipsoid volume formula was compared to PS-TV, determined by the Archimedes' principle. RESULTS: Mean 2D-US-TV (23.9 +/- 14.8 mL) was significantly lower than mean PS-TV (33.4 +/- 20.1 mL). Underestimation was observed in 77% of cases, and it was related to gland multinodularity and/or nodular involvement of the isthmus, while 2D-US-TV matched the PS-TV in the remaining 21 cases (23%). A mathematical formula, to estimate PS-TV from US-TV, was derived using a linear model (Calculated-TV = [1.24 x 2D-US-TV]+ 3.66). Calculated-TV (mean value 33.4 +/- 18.3 mL) significantly (p < 0.01) increased from 21 (23%) to 31 (34%) of the cases that matched PS-TV. In addition, it significantly (p < 0.01) decreased from 77% to 27% the percentage of cases where PS-TV was underestimated as well as the range of the disagreement from 245% to 92%. CONCLUSIONS: This study shows that 2D-US does not provide an accurate estimation of TV and suggests that it can be improved by a mathematical model different from the ellipsoid model. If confirmed in prospective studies, this may contribute to a more appropriate management of thyroid diseases. |
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Authors:
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Pierpaolo Trimboli; Massimo Ruggieri; Angela Fumarola; Michele D'Alò; Andrea Straniero; Amelia Maiuolo; Salvatore Ulisse; Massimino D'Armiento |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Thyroid : official journal of the American Thyroid Association Volume: 18 ISSN: 1050-7256 ISO Abbreviation: Thyroid Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-08-11 Completed Date: 2008-09-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9104317 Medline TA: Thyroid Country: United States |
Other Details:
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Languages: eng Pagination: 879-82 Citation Subset: IM |
Affiliation:
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Department of Experimental Medicine, Sapienza University of Rome, Viale del Policlinico 155, Rome, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Female Humans Male Middle Aged Retrospective Studies Thyroid Gland / anatomy & histology*, ultrasonography* Thyroidectomy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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