| A maternal warm-reactive autoantibody presenting as a positive direct antiglobulin test in a neonate. | |
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MedLine Citation:
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PMID: 15387790 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Autoimmune hemolytic anemia in pregnancy is a rare cause of hemolytic disease of the newborn. This report describes a neonate with a mild hemolytic process and a positive direct antiglobulin test (DAT) presenting as the first manifestations of a maternal warm-reactive autoantibody. A full-term male neonate, blood group O, had a strongly positive DAT and laboratory evidence suggestive of a mild hemolytic process. The neonate's mother was also group O and had a negative antibody screen. Umbilical cord blood testing revealed a panreactive eluate though the antibody was not detected in cord serum. The neonate's mother was also found to have a positive DAT. A panagglutinin was identified in an eluate of her red cells, although the autoantibody could not be detected in her serum by a variety of sensitive techniques. There was no clinical or laboratory evidence of maternal hemolysis. |
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Authors:
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T D Williamson; L H Liles; D P Blackall |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Immunohematology / American Red Cross Volume: 13 ISSN: 0894-203X ISO Abbreviation: Immunohematology Publication Date: 1997 |
Date Detail:
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Created Date: 2004-09-24 Completed Date: 2005-03-15 Revised Date: 2008-04-08 |
Medline Journal Info:
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Nlm Unique ID: 8806387 Medline TA: Immunohematology Country: United States |
Other Details:
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Languages: eng Pagination: 6-8 Citation Subset: - |
Affiliation:
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Blood Bank, The Regional Medical Center at Memphis, Memphis, Tennessee, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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