Document Detail

A map of the major nuclei of the fetal sheep brainstem.
MedLine Citation:
PMID:  17208652     Owner:  NLM     Status:  MEDLINE    
The fetal sheep has been used to investigate a wide range of developmental and pathological processes such as the effect of severe hypoxia, asphyxia, or intrauterine infection on the brain but, until now, there has been no complete description of the normal anatomical organisation of neuronal groups to facilitate interpretation of these studies. In this paper, we describe the major nuclei of the fetal sheep brainstem based on a study of 5 fetal sheep at 140 days of gestation (G140: term is G147). Nuclei were identified with the aid of brain atlases available for other species, and from the previously published, partial descriptions available for the sheep. Fifty-five distinct nuclei were identified after Nissl (thionin) staining, and their caudal and rostral margins were defined. This paper provides an easy reference to the position of the major nuclei within the fetal sheep brainstem, and can be used as a guide for future studies examining the organisation of neuronal populations under normal and pathological conditions in this animal model.
Elaine M Stockx; Colin R Anderson; Susan M Murphy; Ian R C Cooke; Philip J Berger
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-10-27
Journal Detail:
Title:  Brain research bulletin     Volume:  71     ISSN:  0361-9230     ISO Abbreviation:  Brain Res. Bull.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-08     Completed Date:  2007-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7605818     Medline TA:  Brain Res Bull     Country:  United States    
Other Details:
Languages:  eng     Pagination:  355-64     Citation Subset:  IM    
Ritchie Centre for Baby Health Research, Monash Institute of Medical Research, Monash University, Monash Medical Centre, 246 Clayton Rd, Victoria 3168, Australia.
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MeSH Terms
Brain Stem / anatomy & histology*,  embryology*
Fetus / anatomy & histology*,  physiology*
Functional Laterality / physiology
Image Processing, Computer-Assisted

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