| The management of rheumatic diseases in pregnancy. | |
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MedLine Citation:
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PMID: 20337545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pregnancy can create a challenge for physicians caring for women with rheumatic diseases. For many women with rheumatoid arthritis (RA), pregnancy can provide a reprieve from long-term joint pain and inflammation, but others will not experience remission and will continue to need medication. Systemic lupus erythematosus (SLE) may remain quiet in some women, but in others may become more aggressive during pregnancy, putting both mother and foetus at risk. Women with limited scleroderma can do remarkably well, but scleroderma renal crises can be difficult to manage. A third of pregnancies in women with antiphospholipid syndrome (APS) may be refractory to our best therapy. In general, active inflammation from rheumatic diseases poses a stronger threat to the well-being of both mother and foetus than many immunosuppressant medications. Therefore, continued immunosuppression with the least risky medications will allow for the most optimal pregnancy outcomes. |
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Authors:
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K Mitchell; M Kaul; Megan E B Clowse |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Scandinavian journal of rheumatology Volume: 39 ISSN: 1502-7732 ISO Abbreviation: Scand. J. Rheumatol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-26 Completed Date: 2010-04-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0321213 Medline TA: Scand J Rheumatol Country: England |
Other Details:
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Languages: eng Pagination: 99-108 Citation Subset: IM |
Affiliation:
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Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Monitoring Humans Pregnancy Pregnancy Complications / therapy Rheumatic Diseases / therapy* |
| Grant Support | |
ID/Acronym/Agency:
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T32-5T32-AI007217-27/AI/NIAID NIH HHS |
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