Document Detail

The management and natural history of severe dysplasia and carcinoma in situ of the uterine cervix.
MedLine Citation:
PMID:  952784     Owner:  NLM     Status:  MEDLINE    
This report concerns 375 patients seen in Frederiksberg, Denmark, between 1951 and 1972: 103 of them had severe dysplasia and 272 of them carcinoma in situ of the uterine cervix. Thirty patients had no primary treatment: 9 of them developed invasive carcinoma, and 2 of these died; 12 patients had persistent intraepithelial abnormality of the cervix and the other 9 patients showed no abnormality after varying periods of observation. Recurrences after cone biopsy were noted in 9.5 and 10.1 per cent of patients with severe dysplasia and carcinoma in situ respectively, and in 2 per cent of patients who had an in situ carcinoma treated by hysterectomy. This made a total of 15 patients with recurrences. All were ultimately cured although two patients were found to have invasive carcinoma.
C Gad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  83     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-10-20     Completed Date:  1976-10-20     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  554-9     Citation Subset:  AIM; IM    
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MeSH Terms
Carcinoma in Situ / surgery,  therapy*
Cervix Uteri / surgery
Middle Aged
Neoplasm Recurrence, Local / therapy
Precancerous Conditions / surgery,  therapy*
Uterine Cervical Diseases / surgery,  therapy*
Uterine Cervical Neoplasms / surgery,  therapy*

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