Document Detail


The management of amyotrophic lateral sclerosis.
MedLine Citation:
PMID:  19224316     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The terms amyotrophic lateral sclerosis (ALS) or motor neuron disease (MND) refer to a condition characterized by motor system degeneration with relative preservation of other pathways. Although there have been advances in symptomatic treatment, ALS remains an incurable condition. Advances in ALS management prolong survival but simultaneously raise challenging ethical dilemmas for physicians, patients and their families. Here, we review current practice in the management of ALS including pharmacological treatment, nutritional management, respiratory care, and evolving strategies in the management of cognitive impairment.
Authors:
Julie Phukan; Orla Hardiman
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-02-17
Journal Detail:
Title:  Journal of neurology     Volume:  256     ISSN:  1432-1459     ISO Abbreviation:  J. Neurol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-07-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  176-86     Citation Subset:  IM    
Affiliation:
Dept. of Neurology, Beaumont Hospital, and Trinity College Institute of Neuroscience, Dublin 9, Ireland.
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MeSH Terms
Descriptor/Qualifier:
Amyotrophic Lateral Sclerosis / complications,  psychology,  therapy*
Caregivers / ethics,  psychology,  statistics & numerical data
Cognition Disorders / etiology,  psychology,  therapy*
Genetic Predisposition to Disease / genetics
Long-Term Care / ethics,  methods,  psychology
Palliative Care / methods,  standards
Physician-Patient Relations / ethics
Respiration, Artificial / standards
Respiratory Insufficiency / etiology,  physiopathology,  therapy
Withholding Treatment / ethics,  standards

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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