Document Detail

The management of adverse drug reactions: from diagnosis to signal.
MedLine Citation:
PMID:  11878098     Owner:  NLM     Status:  MEDLINE    
Severe adverse reactions (ADR) are uncommon and benefits of drug treatment usually outweigh the disadvantages. Definitions and guidelines for managing adverse drug reactions (ADRs) are proposed mainly with the aim of helping to keep the possibility of ADR at the front of our minds and making the right diagnosis. As spontaneous reporting is a cornerstone in post-marketing surveillance, the reasons for under-reporting are thoroughly analysed. Finally, a reminder is given that communication of information should be encouraged within the medical community and that everyone who is involved in the treatment of patients has an active part to play in the network of pharmacovigilance.
I R Edwards
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Thérapie     Volume:  56     ISSN:  0040-5957     ISO Abbreviation:  Therapie     Publication Date:    2001 Nov-Dec
Date Detail:
Created Date:  2002-03-06     Completed Date:  2002-04-24     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0420544     Medline TA:  Therapie     Country:  England    
Other Details:
Languages:  eng     Pagination:  727-33     Citation Subset:  IM    
WHO Collaborating Centre for International Drug Monitoring, Stora Torget 3, 75320 Uppsala, Sweden.
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MeSH Terms
Adverse Drug Reaction Reporting Systems
Pharmaceutical Preparations / adverse effects*
Reg. No./Substance:
0/Pharmaceutical Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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