| A malaria control program's effect on paediatric transfusion. | |
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MedLine Citation:
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PMID: 20546204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVES: Paediatric malaria is one of the leading causes for blood transfusion in sub-Saharan Africa. Malaria not only causes severe, sometimes life-threatening anaemia, but it leads to the exposure to a blood supply that may result in viral disease transmission. This study determined the frequency of paediatric malaria and transfusion for malaria before and after implementation of a Malaria Control Program in one of Ghana's districts. MATERIALS AND METHODS: Paediatric patients' malaria test results and blood transfusions were reviewed during two time periods: before Malaria Control Program implementation (2003) and after (2009). Results were analysed using descriptive and bivariate statistics. RESULTS: The number of paediatric malaria cases confirmed by laboratory testing declined by 40·7% after implementation of the program. The number of paediatric patients transfused decreased by 12·8% (P<0·005). Of those patients tested for malaria, the frequency of transfusion was lower in 2009 (11·3%) compared to 2003 (24·1%, P<0·005). Gender and age were not associated with altered rates of transfusion. Average haemoglobin was higher in 2009 (10·4±2·0 g/dl) compared to 2003 (8·7±2·1 g/dl, P<0·005). During both periods of study, malaria positive patients who were 0-5 years were more likely to be transfused (47·6% in 2003, 75% in 2009) compared to children 5-9 years (17·3% in 2003, 18·8% in 2009). CONCLUSION: The implementation of malaria control led to fewer paediatric patients with laboratory-confirmed malaria and fewer requiring blood transfusion. Such programs may reduce morbidity and mortality directly, while limiting exposure to blood transfusion. |
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Authors:
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M Delaney; D Somuah |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Vox sanguinis Volume: 99 ISSN: 1423-0410 ISO Abbreviation: Vox Sang. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-15 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0413606 Medline TA: Vox Sang Country: England |
Other Details:
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Languages: eng Pagination: 314-8 Citation Subset: IM |
Copyright Information:
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© 2010 The Author(s). Vox Sanguinis © 2010 International Society of Blood Transfusion. |
Affiliation:
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Puget Sound Blood Center, Seattle, WA, USA. meghand@psbc.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Transfusion* Child Child, Preschool Communicable Disease Control* Female Ghana Hemoglobins / metabolism Humans Infant Infant, Newborn Malaria / blood, epidemiology*, transmission* Male National Health Programs* |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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