Document Detail


Hypertriglycéridémie majeure et syndrome d'activation macrophagique.
MedLine Citation:
PMID:  21464001     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We report the case of a 36-year-old patient admitted for Macrophage Activation Syndrome (MAS), revealed by inflammatory dermo-hypodermal lesions, tumor syndrome, pancytopenia, biological cholestasis, increased lactate dehydrogenase rates and hemophagocytosis in skin biopsies. The patient also exhibited an exponential increase in triglycerides serum levels that reached 22 g/L. The patient died after multiple organ failure. This case illustrates the value of the hypertriglyceridemia in the diagnosis and monitoring of hemophagocytic syndrome but also highlights the difficulty in understanding its pathophysiology especially with several elements that contribute to its aggravation during the evolution of this syndrome.
Authors:
Abdelali Tali; Amal Addebbous; Meryem Rachid; Laila Zougaghi; Nadia Akhdari; Amal Said; Laila Chabaa
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Annales de biologie clinique     Volume:  69     ISSN:  0003-3898     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-4-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984690R     Medline TA:  Ann Biol Clin (Paris)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  117-120     Citation Subset:  -    
Affiliation:
Unité de biochimie clinique, Laboratoire d'analyses médicales, Centre hospitalier universitaire Mohammed VI ; Faculté de médecine et pharmacie, Université cadi Ayyad, Marrakech, Maroc.
Vernacular Title:
Hypertriglycéridémie majeure et syndrome d'activation macrophagique.
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