| Is lung cancer surgery justified in patients with coronary artery disease? | |
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MedLine Citation:
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PMID: 8086174 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Between 1987 and 1992, 21 patients who presented with potentially resectable non-small cell lung cancer and coronary artery disease, underwent a preoperative cardiac catheterization in order to assess the coronary artery anatomy and left ventricular function. There were 20 men and 1 woman whose ages ranged from 57 to 77 years. Patients with triple-vessel disease and poor distal circulation or impaired ventricular function (n = 2) were excluded from myocardial revascularization and pulmonary surgery. Patients with a curable left-main or triple-vessel disease (group I) first underwent surgical (n = 3) or transluminal (n = 4) myocardial revascularization. The remaining patients presented with single- or double-vessel disease, and were operated on without prior myocardial revascularization (group II; n = 12). The thoracic procedures consisted of exploratory thoracotomy in two cases, lung-sparing resection in one, lobectomy in ten, bilobectomy in one and pneumonectomy in five. The overall mortality and morbidity rates were 5.3% and 31.6%, respectively. Four patients (21%) experienced postoperative cardiac complications: fatal myocardial infarction (n = 1) and dysrhythmia (n = 2) in three group II patients (25%), and transient myocardial ischemia in one group I patient (14.3%). The overall survival rate at 5 years was 57.4% for the 17 patients who underwent resection of their cancer. We conclude that 1) lung surgery in patients with non-small cell lung cancer and coronary artery disease is justified in selected cases, 2) previous myocardial revascularization appears to confer protection against the development of postoperative cardiac morbidity. |
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Authors:
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P Thomas; R Giudicelli; J C Guillen; P Fuentes |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery Volume: 8 ISSN: 1010-7940 ISO Abbreviation: Eur J Cardiothorac Surg Publication Date: 1994 |
Date Detail:
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Created Date: 1994-10-18 Completed Date: 1994-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8804069 Medline TA: Eur J Cardiothorac Surg Country: GERMANY |
Other Details:
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Languages: eng Pagination: 287-91; discussion 292 Citation Subset: IM |
Affiliation:
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Department of Thoracic Surgery, Sainte-Marguerite Hospital, Marseille, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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complications,
surgery Aged Carcinoma, Large Cell / complications, surgery Carcinoma, Non-Small-Cell Lung / complications, mortality, surgery* Carcinoma, Squamous Cell / complications, surgery Coronary Disease / complications*, surgery Female Humans Lung Neoplasms / complications, mortality, surgery* Male Middle Aged Myocardial Revascularization Pneumonectomy Postoperative Complications Prognosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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