Document Detail


The lubricating activity of human synovial fluids.
MedLine Citation:
PMID:  6721888     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The lubricating abilities of human synovial fluids were measured using a rotating cartilage-on-glass apparatus. A total of 247 human fluids were lubrication-tested. Of these, 20 of the 180 knee fluids from patients with degenerative/traumatic joint disease lubricated less well than normal bovine synovial fluid. The remainder of the fluids from the knee and other joints were equivalent to normal bovine synovial fluid in their lubricating properties. The concentrations of hyaluronic acid, protein, and sialic acid and the relative viscosity of 117 human fluid samples were determined, but no relationships between the gross composition and the lubricating abilities were apparent.
Authors:
D A Swann; K J Bloch; D Swindell; E Shore
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  27     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-06-06     Completed Date:  1984-06-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  552-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Glycoproteins / physiology
Humans
Hyaluronic Acid / analysis
Lubrication
N-Acetylneuraminic Acid
Proteins / analysis
Sialic Acids / analysis
Synovial Fluid / analysis,  physiology*
Viscosity
Grant Support
ID/Acronym/Agency:
AM19834/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
0/Glycoproteins; 0/Proteins; 0/Sialic Acids; 131-48-6/N-Acetylneuraminic Acid; 9004-61-9/Hyaluronic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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