| A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic. | |
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MedLine Citation:
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PMID: 20064146 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The UK influenza pandemic plan predicts up to 750,000 additional deaths with hospitals prioritising patients against inadequate resources. We investigated three prototype low-cost, gas-efficient, pneumatic ventilators in a test lung model at different compliance and rate settings. Mean (SD) oxygen consumption was 0.913 (0.198) and 1.119 (0.267) l.min(-1) at tidal volumes of 500 ml and 700 ml respectively. Values of F(I)o(2) increased marginally as lung compliance reduced, reflecting the increased ventilator workload and consequent increased enrichment of breathing gas by waste oxygen from the pneumatic mechanism. We also demonstrated that a stable nitric oxide concentration could be delivered by this design following volumetric principles. It is possible to make a gas-efficient ventilator costing less than 200 pounds from industrial components for use where oxygen is available at 2-4 bar, with no pressurised air or electrical requirements. Such a device could be mass-produced for crises characterised by an overwhelming demand for mechanical ventilation and a limited oxygen supply. |
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Authors:
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D Williams; S Flory; R King; M Thornton; J Dingley |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2010-01-07 |
Journal Detail:
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Title: Anaesthesia Volume: 65 ISSN: 1365-2044 ISO Abbreviation: Anaesthesia Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-18 Completed Date: 2010-04-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: England |
Other Details:
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Languages: eng Pagination: 235-42 Citation Subset: AIM; IM |
Affiliation:
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Department of Anaesthetics, Morriston Hospital, Swansea, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Disease Outbreaks Emergencies Equipment Design Great Britain / epidemiology Humans Lung Compliance Oxygen Consumption* Respiratory Insufficiency / epidemiology, physiopathology, therapy* Tidal Volume Ventilators, Mechanical* |
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