Document Detail

The loud first heart sound in left atrial myxoma.
MedLine Citation:
PMID:  6477778     Owner:  NLM     Status:  MEDLINE    
The interrelation between the loudness of the first heart sound, the time interval from the Q wave to the onset of the first heart sound (QM1), and the mitral valve closure rate was studied in nine patients presenting with left atrial myxomata. In seven patients the first heart sound was loud preoperatively and was associated with delayed mitral valve closure. After removal of the myxoma the onset of mitral valve closure returned towards normal, the mitral valve closure rate was reduced, and the first heart sound became softer. In two patients the first heart sound was normal before and after operation as were both the time of onset of mitral valve closure and the mitral valve closure rate. In neither of these patients did the myxoma completely fill the mitral orifice during diastole. The loud first heart sound in left atrial myxoma is a useful clinical sign, and intensity is directly related to the delay in onset of closure of mitral leaflets.
A H Gershlick; G Leech; P G Mills; A Leatham
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  52     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-11-09     Completed Date:  1984-11-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  403-7     Citation Subset:  AIM; IM    
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MeSH Terms
Heart Atria
Heart Auscultation*
Heart Neoplasms / diagnosis,  physiopathology*,  surgery
Heart Sounds*
Middle Aged
Mitral Valve / physiopathology
Myxoma / diagnosis,  physiopathology*,  surgery

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