| A longitudinal study of red cell enzymes in infants of low birth weight. | |
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MedLine Citation:
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PMID: 1179794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A longitudinal study of red cell enzyme activity in newborn infants of low birth weight has been conducted over the first 2 months of life. The enzymes investigated are acetylcholinesterase (EC 3.1.3.7), an integral part of the red cell membrane and subnormal in ABO hemolytic disease of the newborn; and glucose-6-phosphate dehydrogenase (EC 1.1.1.49), an intracellularly-located, sex-linked enzyme, implicated in neonatal jaundice and of significance in drug-induced hemolytic anemias. Acetylcholinesterase activity, which is lower in normal full-term infants and in low birth weight infants than in adults, was further diminished during the initial weeks of life of the infants of low birth weight and the higher levels of activity, characteristic of adult red cells, had not appeared by 2 months of age. By contrast, red cell glucose-6-phosphate dehydrogenase activity, which is higher in full-term newborn infants and in infants of low birth weight than in adults, did not diminish as a function of age and the lower adult levels were not discernible by 2 months of life. |
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Authors:
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F Herz; E Kaplan; E S Scheye |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Zeitschrift für Kinderheilkunde Volume: 120 ISSN: 0044-2917 ISO Abbreviation: Z Kinderheilkd Publication Date: 1975 Sep |
Date Detail:
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Created Date: 1975-12-28 Completed Date: 1975-12-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7604363 Medline TA: Z Kinderheilkd Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 217-21 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetylcholinesterase
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blood Age Factors Birth Weight* Cell Membrane Erythrocytes / enzymology* Glucosephosphate Dehydrogenase / blood Humans Infant, Newborn Infant, Premature* |
| Chemical | |
Reg. No./Substance:
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EC 1.1.1.49/Glucosephosphate Dehydrogenase; EC 3.1.1.7/Acetylcholinesterase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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